On The MONEY With These 13 Best Enzyme Cleaners For Cat Urine

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“My cat is pooping on the floor; what is the best enzyme cleaner for cat urine?” This is a question that many pet parents find themselves asking. It can be overwhelming if you’ve ever had to deal with the stench of cat urine. But don’t worry. We’ve got you covered.

Your best bet is to use an enzymatic cleaner. Enzymatic cleaners break down the molecules in urine, eliminating the odor. There are a variety of enzymatic cleaners on the market, so we’ve compiled a list of the 13 best enzyme cleaners for cat urine to help you find the perfect one for your needs.

Cat urine on the floor

What is an Enzyme Cleaner?

An enzyme cleaner is a cleaning solution that uses enzymes to break down and remove stains and odors. Enzyme cleaners clean pet stains, food stains, and other types of messes. These cleaners break down the proteins and other organic materials that cause stains and odors.

Enzyme cleaners are safe to use around pets and children. They are also biodegradable and non-toxic, making them a more environmentally friendly option than other types of cleaners.

Our Favorite Enzyme Cleaner

Before we get into the nitty-gritty of enzyme cleaners, we want to let you in on our favorite. We’ve tried a lot of different cleansers, and hands down, our favorite is the Rocco & Roxie Oxy Stain Remover .

This cleaner is professional grade, and it’s highly effective at removing stains and odors. It’s also safe to use around pets and children.

Made with natural enzymes that break down the odor-causing molecules in urine, this enzyme cat pee cleaner is excellent for both fresh and old stains. It’s also safe on various surfaces, including carpets, upholstery, clothing, and hardwood floors.

Keep reading to learn more about enzymatic cleaners and how they work. You’ll also find a buyer’s guide with tips on what to look for when purchasing an enzyme cleaner and a list of the 13 best enzyme cleaners for cat urine.

How to Stop a Cat From Pooping on the Floor

You can do a few things to stop your cat from pooping on the floor. Here’s what we recommend:

Rule Out Any Medical Problems

If your cat is pooping on the floor, it could be a sign of a medical problem. If your cat is pooping outside of the litter box, make an appointment with your veterinarian to rule out any health problems.

Clean the Litter Box Regularly

Cats are clean creatures, and they prefer a clean litter box. If the litter box is dirty, your cat may be reluctant to use it. Make sure to scoop the litter box daily and change the litter completely at least once a week. If you have more than one cat, you may need to clean the litter box more often.

Provide Enough Litter Boxes

Having enough litter boxes for the number of cats in your home is essential. The general rule of thumb is to have one litter box per cat plus one extra.

So, if you have two cats, you should have three litter boxes. If you have four cats, you should have five litter boxes, and so on. This will give your cats plenty of options and reduce the chances of them pooping on the floor.

Choose the Right Litter 

Not all litters will work for all cats. Some cats prefer clumping litter, while others prefer non-clumping litter. You may need to experiment with different types of litter to find one your cat likes.

Additionally, some cats prefer covered litter boxes, while others prefer uncovered litter boxes. If you’re not sure what type of litter your cat likes, ask your veterinarian for recommendations.

Consider a Litter Box Liner 

Litter box liners can make cleaning the litter box easier. Liners also help to keep the litter box clean and can extend the time between changing the litter. 

There are a variety of liners on the market, so be sure to choose one compatible with the type of litter you are using.

Keep the Litter Box in a Quiet Area 

Cats like to have a little privacy when they use the litter box. 

Choose a quiet area of the house for the litter box, and make sure it’s not near a busy room or loud appliances. 

You should also avoid putting the litter box in an area where your cat feels threatened or scared. 

Reward Good Behavior 

Whenever your cat uses the litter box, be sure to praise them. You can also give them a treat or toy as a reward. Rewarding your cat for using the litter box will help to reinforce this behavior.

How We Tested Our Picks

To narrow down our list of enzyme cleaners for cat urine, we purchased 23 different products. 

We looked for enzyme cleaners that were effective at removing stains and odors, safe to use around pets and children, and easy to use. 

We also considered each product’s price and whether or not it came with a money-back satisfaction guarantee. 

To test each cleaner, we used them to clean up cat urine stains on various surfaces, including carpet, hardwood floors, and tile. 

We also sprayed them on fabrics and let them sit for a few minutes to see if they would remove the cat urine smell. 

Finally, we looked at the ingredients in each cleaner to see if they were safe to use around pets and children. 

Of the 23 cleaners we tested, only 13 met our criteria and made our final cut.

Why Trust Us

I Love Veterinary has a team of experts passionate about pets and pet care. Our goal is to provide you with the best possible information so you can make the best decisions for your pet. 

We research and test products, so you don’t have to, and we only recommend products we believe in. We never accept free products or kickbacks in exchange for a positive review.

Additionally, our editorial team consists of animal lovers committed to providing accurate and helpful information. From vet techs and professional groomers to animal shelter workers and pet parents, we have a wide range of expertise on our team.

We understand the unique bond between humans and animals, and we’re here to help you care for your pet to the best of your ability. So, if you’re looking for the best cat urine remover, you can trust that our team has thoroughly vetted each of the products on our list and that we only recommend products we believe in.

How Do Enzymatic Cleaners Work?

As the name suggests, enzymatic cleaners rely on enzymes to break down stains and odors. 

Enzymes are proteins that act as catalysts to start or accelerate chemical reactions. 

In the case of enzymatic cleaners, the enzymes break down the organic matter in stains and odors, rendering them ineffective. 

Most enzymatic cleaners also contain surfactants, chemicals that lower the surface tension of water, allowing it to penetrate surfaces more easily. 

This helps the cleaner reach the stain or odor deeper and break it down more effectively.

Cat in Litter Box

An Overview of Our Top Picks

  1. Rocco & Roxie Oxy Stain Remover  (Best Overal Enzyme Cleaner for Cat Urine)
  2. OxiClean Carpet and Area Rug Stain Remover Spray  (Best for Area Rug)
  3. Carbona Oxy-Powered 2-in-1 Carpet Cleaner  (Best for Carpets)
  4. Shout Carpet Stain Remover And Odor Eliminator Spray  (Best Affordable)
  5. Rocco & Roxie Stain & Odor Eliminator for Strong Odor  (Best for Stains)
  6. The Spruce Pet Stain & Odor Remover - Plant-Derived Enzyme-Based Cleaner  (Best Scented)
  7. Scotchgard OXY Pet Carpet & Fabric Spot & Stain Remover  (Best for Fabrics)
  8. Biokleen Bac-Out Pet Stain Remover  (Best Bio-Active Formula)
  9. Pet Stain & Odor Miracle - Enzyme Cleaner  (Best for Multi-Surface Use)
  10. Simple Solution Extreme Pet Stain and Odor Remover  (Best for Set-In Stains)
  11. BUBBAS Super Strength Enzyme Cleaner  (Best for Commercial Use)
  12. ANGRY ORANGE Pet Odor Eliminator  (Best Odor Eliminator)
  13. Simple Solution Yard Odor Away! Hose Spray Concentrate  (Best for Outdoors)
Carbona Oxy-Powered 2-in-1 Carpet Cleaner, 27.5 Ounces - Pack of 2
Rocco & Roxie Oxy Stain Remover - Oxygen Powered Carpet Cleaner Spray - Spot Cleaner for Upholstery, Couch, Laundry, Rug, Clothes, Car Seat, Mattress, Sofa, and More. - Pet & Baby Stains
Angry Orange Pet Odor Eliminator for Strong Odor - Citrus Deodorizer for Strong Dog or Cat Pee Smells on Carpet, Furniture & Indoor Outdoor Floors - 24 Fluid Ounces - Puppy Supplies
Product name
Carbona Oxy-Powered 2-in-1 Carpet Cleaner, 27.5 Ounces – Pack of 2
Rocco & Roxie Oxy Stain Remover – Oxygen Powered Carpet Cleaner Spray – Spot Cleaner for Upholstery, Couch, Laundry, Rug, Clothes, Car Seat, Mattress, Sofa, and More. – Pet & Baby Stains
Angry Orange Pet Odor Eliminator for Strong Odor – Citrus Deodorizer for Strong Dog or Cat Pee Smells on Carpet, Furniture & Indoor Outdoor Floors – 24 Fluid Ounces – Puppy Supplies
Price
$16.20
$19.97
$15.29
Carbona Oxy-Powered 2-in-1 Carpet Cleaner, 27.5 Ounces - Pack of 2
Product name
Carbona Oxy-Powered 2-in-1 Carpet Cleaner, 27.5 Ounces – Pack of 2
Price
$16.20
Buy Now
Rocco & Roxie Oxy Stain Remover - Oxygen Powered Carpet Cleaner Spray - Spot Cleaner for Upholstery, Couch, Laundry, Rug, Clothes, Car Seat, Mattress, Sofa, and More. - Pet & Baby Stains
Product name
Rocco & Roxie Oxy Stain Remover – Oxygen Powered Carpet Cleaner Spray – Spot Cleaner for Upholstery, Couch, Laundry, Rug, Clothes, Car Seat, Mattress, Sofa, and More. – Pet & Baby Stains
Price
$19.97
Buy Now
Angry Orange Pet Odor Eliminator for Strong Odor - Citrus Deodorizer for Strong Dog or Cat Pee Smells on Carpet, Furniture & Indoor Outdoor Floors - 24 Fluid Ounces - Puppy Supplies
Product name
Angry Orange Pet Odor Eliminator for Strong Odor – Citrus Deodorizer for Strong Dog or Cat Pee Smells on Carpet, Furniture & Indoor Outdoor Floors – 24 Fluid Ounces – Puppy Supplies
Price
$15.29
Buy Now

Your Cat Enzyme Cleaner Shopping Guide

When it comes to finding the best enzyme cleaner for cat urine, there are a few things you’ll want to keep in mind. Here’s what you should consider before making your purchase.

Surface Use

One of the first things you’ll want to consider is what surfaces you’ll be using the cleaner on. 

If you’re only going to be using it on hard surfaces, like tile or linoleum, you won’t need a cleaner that’s as strong as the one you would use on carpet or upholstery. 

However, if you’re looking for a cleaner that you can use on multiple surfaces, you’ll want to make sure you choose one versatile enough to work on both hard and soft surfaces.

When testing cleaners, we looked at how well they worked on hard and soft surfaces. We found that the best cleaners could effectively clean both types of surfaces.

Active Ingredients

The active ingredients in enzyme cleaners effectively remove stains and odors. 

When testing cleaners, we looked at the active ingredients to see if they were effective at breaking down stains and odors. 

We also examined whether the active ingredients are safe for pets and children. We only recommend cleaners that are safe for both pets and children.

When looking for the best enzyme cleaner for cat urine, you’ll want to ensure that the active ingredients effectively break down stains and odors. 

You’ll also want to ensure that the active ingredients are safe for pets and children. If your pet or any of your family members have allergies, you’ll want to ensure that the cleaner you choose is unscented.

Color Safe Test

Another thing to consider when choosing an enzymatic cleaner is whether or not it’s color safe. Most enzymatic cleaners are labeled color safe, but we always like to test cleaners to be sure. 

To test for colorfastness, we apply the cleaner to an inconspicuous area of the fabric or carpet and wait for it to dry. 

If there is no change in color after the cleaner has dried, we consider it color safe.

When choosing an enzyme cleaner, you’ll want to ensure that it’s labeled color safe. To be sure, you can also test the cleaner on an inconspicuous area of the fabric or carpet.

Ease of Application

Let’s face it; no one wants to spend hours trying to remove a stain. Most of us would rather avoid the whole process entirely. 

That’s why choosing a cleaner that’s easy to apply is essential. 

Enzyme cleaners packed in a spray bottle are usually the easiest to apply. Spray bottles are ideal because they allow you to target the stain without oversaturating the area. Also, if your target is a crack in the tile or a hard-to-reach spot, a spray bottle will make it easier to apply the enzyme cleaner. 

For large areas or heavily soiled areas, you may want to choose an enzyme cleaner that you can mix with water. These cleaners usually come in a concentrate that you can dilute with water before applying.

Non-Toxic Ingredients

The best enzyme cleaners are non-toxic and safe for you, your family, and your pets. Always read the label before purchasing an enzyme cleaner to ensure it doesn’t contain harmful chemicals.

You’ll also want to ensure that the enzyme cleaner you choose is safe for the environment. Look for cleansers that are biodegradable and free of harmful chemicals.

Timeframe

Stains can be stubborn, especially if they’ve been around for a while. Old stains may require multiple applications of enzyme cleaner before they disappear entirely. New stains will usually disappear after one or two applications.

When choosing an enzyme cleaner, you’ll want to consider how long it will take to remove the stain. That’s why reading the label is essential before purchasing an enzyme cleaner. 

The best enzyme cleaners will clearly state whether or not they’re effective on old or new stains.

Scent

Some enzyme cleaners have a strong scent that can be overwhelming. If you’re sensitive to smells or have allergies, you’ll want to make sure you choose an unscented enzyme cat pee cleaner.

Most cats don’t like the smell of citrus or lavender, so these scents can help keep your cat away from the area you’ve treated. 

If you have multiple pets, you may want to choose an unscented cleaner so that your pets don’t fight over who gets to sleep in the clean spot.

Packaging

The packaging of an enzyme cleaner can be just as important as the ingredients. Some spray bottles leak or drip, making it challenging to apply the cleaner. 

Other cleaners come in a bottle that’s difficult to open or stop dispensing the cleaner after a few uses. 

Always read the reviews before purchasing an enzyme cleaner to ensure you’re getting a high-quality product.

Our Feline Enzyme Cleaner Reviews

Rocco & Roxie Oxy Stain Remover  (Best Overal Enzyme Cleaner for Cat Urine)

Key Features

  • Brand: Rocco & Roxie Supply Co.
  • Recommended uses: Rug, carpet, upholstery, laundry
  • Item form: Liquid
  • Volume: 1 quart (946 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Multipurpose cleaner
  • Scent/s: Mint scent

When looking for an enzyme cleaner to handle any stain, we knew we needed to find one powerful enough to remove even the most stubborn stains. We’re such fans of the Rocco & Roxie Oxy Stain Remover. 

Our top pick has activated oxygen, which is a powerful oxidizing agent. This means it can break down the molecules in stains, making them easier to remove. We tested the enzymatic cleaner on rugs, carpets, and upholstery. This cleaner worked great on all three surfaces, and it was able to remove stains that other cleaners couldn’t touch. 

We also appreciate that the Rocco & Roxie Oxy Stain Remover is chlorine-free and color safe. So you don’t have to worry about bleaching your carpets or upholstery. The Carpet and Rug Institute (CRI) has also certified this cleaner, so you can be sure it’s safe for your carpets and rugs. 

What we love about this cleaner is that it’s multipurpose. Not only can you use it on carpets and upholstery, but you can also use it on clothing, pet beds, and other fabrics. 

The Rocco & Roxie Oxy Stain Remover comes in a non-aerosol bottle, which we appreciate. We’ve had problems with other spray bottles leaking or dribbling, but that wasn’t an issue with this cleaner. You can also easily control how much cleaner you dispense, which is great if you’re trying to remove a small stain. 

For heavier stains, we recommend pre-treating the area with this cleaner. Just spray the cleaner on the stain and let it sit for 5 to 10 minutes before blotting it up with a clean cloth. If the color is still visible, you can repeat the process until it disappears.

We should also mention that this cleaner has a minty scent that we enjoy. If you have multiple pets, the fresh scent can help keep them from re-soiling the area.

What We LikedWhat We Didn’t Like
-Powerful formula removes tough stains
-The non-aerosol bottle doesn’t leak or dribble
-Besides pet stains, it can handle other household stains
-CRI-certified safe for carpets and rugs
-Asthmatic reviewers noted that it has a strong smell

OxiClean Carpet and Area Rug Stain Remover Spray  (Best for Area Rug)

Key Features

  • Brand: OxiClean
  • Recommended uses: Carpets, rugs
  • Item form: Spray
  • Volume: 24 fluid ounces (710 milliliters)
  • Unit count: 2
  • Kid and Pet-friendly: Yes
  • Cleaner type: Carpet and rug cleaner

Our next pick is the OxiClean Carpet and Area Rug Stain Remover Spray. Specifically designed for carpets and rugs, this product is also safe for kids and pets. Our tester noted that this product eliminates pet odors quickly, and it’s easy to use. Simply spray the affected area and blot it with a clean cloth.

We sprayed the formula on a dry carpet stain and found it worked quickly to break down the mess. In addition, our tester found that this product is excellent for light to moderate colors. We recommend trying another product on our list if you have a more stubborn stain.

We also like that this product is available in a two-pack, so you can keep one on hand for quick cleanup jobs.

OxiClean is one of the most famous names in stain removal, and for a good reason. This carpet and area rug stain remover spray is tough on stains but gentle on carpets and rugs.

What We LikedWhat We Didn’t Like
-Eliminates urine scent
-Eliminates pet odors quickly
-Easy to use
-Safe for kids and pets
-Available in a two-pack
-Some users say the spray nozzle leaks
-It contains hydrogen peroxide, which can bleach some fabrics
-It takes a more extended period to saturate the stain

Carbona Oxy-Powered 2-in-1 Carpet Cleaner  (Best for Carpets)

Key Features

  • Brand: Carbona
  • Recommended uses: Washing
  • Item form: Liquid
  • Volume: 27 fluid ounces (813 milliliters)
  • Unit count: 2
  • Kid and Pet-friendly: Yes
  • Cleaner type: Carpet cleaner
  • Scent/s: No scent

Talk about a powerhouse cleaner! The Carbona Oxy-Powered 2-in-1 Carpet Cleaner is excellent for removing tough stains from carpets. When we tested this product, we could remove coffee, pet, and even red wine stains.

What we loved most about this product is how convenient it is. The 2-in-1 design means that you can use it as a brush or a sponge. The product features a sponge with bristles that work together to loosen and lift dirt and stains from carpets. So, whether you have a light stain or a heavy-duty stain, this product can handle it.

While this product is excellent for carpets, using it on other fabrics is not recommended. The manufacturer suggests that you do not use this product on velvet,  silk, Haitian Cotton, or other fabrics harmed by water. Out of curiosity, we tested it on a silk scarf, and it did leave a watermark. So, if you do use it on delicate fabrics, be sure to spot-test first.

Overall, Carbona Oxy-Powered 2-in-1 Carpet Cleaner impressed us with its ability to remove tough stains quickly and easily. For maximum convenience, we recommend blotting the stain before using the cleaner.

What We LikedWhat We Didn’t Like
-The 2-in-1 design is convenient
-Can remove fresh stains quickly
-Kid and pet-friendly
-Available in a pack of 2
-Not recommended for use on delicate fabrics
-More than one application may be necessary for set-in stains

Shout Carpet Stain Remover And Odor Eliminator Spray  (Best Affordable)

Key Features

  • Brand: SHOUT
  • Recommended uses: Set in stains
  • Item form: Spray
  • Volume: 32 fluid ounces (946 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Carpet cleaner

For those looking for a fast-acting but affordable carpet cleaner, SHOUT’s Carpet Stain Remover and Odor Eliminator Spray is the best choice. This powerful spray removes pet stains and eliminates odors in under 10 minutes, making it the fastest stain remover on our list.

This carpet cleaner is also one of the most affordable, costing less than $10 per bottle. SHOUT’s carpet cleaner is easy to use; just spray it on the stain, let it sit for 3-5 minutes, blot with a clean cloth, and vacuum when dry.

SHOUT’s carpet cleaner is also preventative; it contains ingredients that work together to discourage pets from re-marking the same spot. This is an excellent feature for those who are potty training their pets or have older pets with incontinence issues.

Whether fresh or set in, SHOUT’s Carpet Stain Remover and Odor Eliminator Spray can handle it. However, we recommend using this cleaner on fresh stains as soon as possible for the best results. You may need to spray and blot several times to remove set-in stains.

What We LikedWhat We Didn’t Like
-Fast-acting
-Prevents re-marking
-Easy to use
-Affordable
-Eliminates odor
-Kid and pet-friendly
-Not as effective on set-in stains

Rocco & Roxie Stain & Odor Eliminator for Strong Odor  (Best for Stains)

Key Features

  • Brand: Rocco & Roxie Supply Co.
  • Recommended uses: Carpet stain remover for cats and dog pee
  • Item form: Liquid
  • Volume: 32 fluid ounces (946 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Multipurpose enzymatic cleaner

Another great choice from Rocco & Roxie, this time, their Stain & Odor Eliminator for Strong Odors is the best enzymatic cleaner for removing pet urine stains. As with our top pick, this product is Carpet and Rug Institute (CRI) certified, meaning it’s safe to use on all types of carpets.

We tested this enzyme cat pee cleaner on several surfaces, including hardwood floors, laminate, tile, and clothing. While it did a great job on all surfaces, we were incredibly impressed with how well it cleaned the carpet. This is likely because it contains natural enzymes, which are effective at breaking down stains.

In addition to being a tremendous enzyme-based cleaner, this product is also chlorine-free and color safe. This means it won’t damage your carpet or furniture and is safe to use around pets and children.

One thing to note is that this cleaner does contain some scent, so if you’re sensitive to smells, you may want to choose another product. Our tester found the odor to be unpleasant but not overwhelming.

Other than that, this is an excellent enzyme cleaner that’s sure to remove even the most stubborn pet stains. Backed by a 100% satisfaction guarantee, it’s a perfect choice for anyone looking for the best enzyme cleaner for cat urine. And one final plus? Amazon rates it as the #1 best seller in small animal odor and stain removers!

What We LikedWhat We Didn’t Like
-Carpet and Rug Institute (CRI) certified
-Safe to use around pets and children
-Excellent at removing pet stains
-100% satisfaction guarantee
-Leaves a scent behind

The Spruce Pet Stain & Odor Remover - Plant-Derived Enzyme-Based Cleaner  (Best Scented)

Key Features

  • Brand: The Spruce
  • Recommended uses: For hardwood, tile, carpets, and upholstery
  • Item form: Liquid
  • Volume: 17 fluid ounces (502.75 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Stain and odor remover
  • Scent/s: Fresh neroli, apple, and orchid

When it comes to finding the best enzyme cleaner for cat urine, you want something practical and have a pleasant scent. That’s why we love The Spruce Pet Stain & Odor Remover. This plant-based enzyme cleaner is excellent for cleaning up cat urine messes on surfaces like tile, wood, carpets, and upholstery.

What we love most about this enzyme cleaner is the aromatherapeutic blend of neroli, apple, and orchid that leaves your home smelling fresh and clean. Our tester found the scent so pleasant that she enjoyed using the product.

Another great feature of this enzyme cleaner is its cruelty-free and Leaping Bunny Certified. This means the making of this product did not involve animal testing. So, if you’re looking for an effective and humane cleaner, this is the one for you.

The adjusted pH level is also ideal for households with pets. This ensures that the cleaner will not harm your pets or surfaces in your home.

Additionally, the Spruce Pet Stain & Odor Remover is free of dyes, caustics, synthetic fragrances, phthalates, parabens, chlorine, formaldehyde, triclosan, or phosphates. This makes it a safe choice for households with children or pets.

The only downside of this enzyme cleaner is that the sprayer can sometimes get clogged. However, our tester found that a quick rinse under hot water usually did the trick.

What We LikedWhat We Didn’t Like
-Plant-based and enzyme-powered
-Cruelty-free
-Leaping Bunny Certified
-It has a pleasant scent
-pH-balanced
-A clogged sprayer can be an issue

Scotchgard OXY Pet Carpet & Fabric Spot & Stain Remover  (Best for Fabrics)

Key Features

  • Brand: Scotchgard
  • Recommended uses: Carpet, upholstery
  • Item form: Liquid
  • Volume: 26 fluid ounces (769 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Carpet cleaner

When it comes to fabrics, you want an effective and gentle cleaner. That’s why we love Scotchgard OXY Pet Carpet & Fabric Spot & Stain Remover. We tested this 2-in-1 upholstery and carpet enzyme cleaner on furniture, clothing, and carpets, and it did an excellent job of removing pet stains without damaging the fabric.

Our reviewer notes that this enzyme cleaner works well on all pet stains, including urine, feces, vomit, and mud. It also does a great job on tough human stains like red wine, dirt, oil, and makeup. This cleaner will not leave any sticky residue when used as directed.

One of the best things about this enzyme cleaner is that it helps to prevent future stains. This is because the Scotchgard Protector in the cleanser works to block stains from setting in. We also appreciate that this cleaner is safe to use around pets and children.

Scent removal is the only thing we didn’t love about this cleaner. While it did a great job removing the stain, it didn’t do much to remove the pet odor. However, many other reviewers noted that this enzyme cleaner is excellent at removing pet odors.

What We LikedWhat We Didn’t Like
-Works on all types of stains
-Prevents future stains
-Safe to use around pets and children
-It doesn’t leave behind a sticky residue
-Ideal on most fabrics
-Not very effective at removing pet odors

Best Bio-Active Formula: Biokleen Bac-Out Pet Stain Remover 

Amazon’s Choice for “Bac-Out Pet Stain and Odor Eliminator”

Key Features

  • Brand: Biokleen
  • Recommended uses: Floor, rug, carpet, furniture
  • Item form: Spray
  • Volume: 32 fluid ounces (946 milliliters)
  • Unit count: 2
  • Kid and Pet-friendly: Yes
  • Cleaner type: Multipurpose cleaner
  • Scent/s: Lavender lime

Regarding enzyme cleaners, you can’t go wrong with Biokleen Bac-Out Pet Stain Remover. This lavender and citrus-scented spray is Amazon’s choice for “Bac-Out pet stain and odor eliminator,” It works great on carpets, rugs, and upholstery.

This cleaner impressed our experts with its ability to remove set-in stains and odors. One of our experts, Jason, has a white carpet in his home. After testing out this cleaner, he was able to get rid of several set-in food and drink stains that had been there for months. He says the cleaner has a “pleasant smell” and did not leave any residue or stickiness behind.

Our experts also like that this cleaner is pet and kid-friendly, as it’s made with natural ingredients and doesn’t contain any harsh chemicals. This cleaner is also eco-friendly and safe on multiple surfaces and fabrics. You can even use it on your car upholstery or laundry to remove pet stains and odors from clothing.

One thing to note is that this cleaner does have a strong lavender scent. If you’re not a fan of lavender, you may want to try another enzyme cleaner on our list. But if you don’t mind the scent, this cleaner is an excellent choice for removing pet stains and odors.

What We LikedWhat We Didn’t Like
-Uses bio-enzymatic cleaning
-Safe for use on multiple surfaces and fabrics
-Eco-friendly and plant-based
-Green Seal certified
-No harsh chemicals or phosphates
-Poorly designed bottle

Pet Stain & Odor Miracle - Enzyme Cleaner  (Best for Multi-Surface Use)

Key Features

  • Brand: Sunny & Honey
  • Recommended uses: For carpets, rugs, car upholstery, mattress, furniture, pet beds, concrete floor, tile
  • Item form: Spray
  • Volume: 32 fluid ounces (946 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Stain and odor remover
  • Scent/s: Spring mint scent

For a versatile enzyme cleaner that you can use on multiple surfaces, you’ll want to check out Pet Stain & Odor Miracle – Enzyme Cleaner by Sunny & Honey. This Spring Mint-scented spray is perfect for cleaning up any pet messes, big or small. And it’s not just for carpets and fabrics – you can use this miracle cleaner on leather, couches, pet beds, crates, litter boxes, car upholstery, and mats.

What amazed our testers the most was that this enzymatic solution is also great for cleaning up outside. This cleaner can remove pet stains and odors if you have artificial grass or turf, a deck, or a patio. We used it on our patio furniture, which worked like a charm!

This enzymatic cleaner is biodegradable, so you can feel good about using it around your home. It also contains no harsh chemicals or toxins, and the essential oils give it a refreshing spring mint scent.

If, for any reason, you’re not satisfied with this product, you can take advantage of the 60-day return policy. This means that Sunny & Honey are so confident in their product that they’ll give you your money back if you’re not happy.

Finally, this product is CRI certified. This means that the Carpet and Rug Institute, the leading authority on carpet cleaning, tested and approved this product. So you know it’s safe and effective for all carpets and rugs.

What We LikedWhat We Didn’t Like
-You can use it on multiple surfaces, both inside and outside
-Biodegradable and non-toxic
-It has a refreshing spring mint scent
-100% money-back satisfaction guarantee
-CRI certified
-Strong smell for those with sensitivities
-Expensive

Simple Solution Extreme Pet Stain and Odor Remover  (Best for Set-In Stains)

Amazon’s choice in Dog Odor Removers by Simple Solution

Key Features

  • Brand: Simple Solution
  • Recommended uses: Carpet, bedding, upholstery, fabric toys, clothing
  • Item form: Spray
  • Volume: 32 fluid ounces (946 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Stain and odor remover

When it comes to set-in stains and odors, you need a powerful enzymatic cleaner to break down the mess. While all the enzyme cleaners on our list are effective, our testers found that Simple Solution Extreme Pet Stain and Odor Remover worked the best. When used as directed, this stain and odor remover eliminates the toughest pet stains and odors, including urine, vomit, blood, and feces.

This powerful enzyme cleaner comes in a convenient spray bottle, and you can use it on various surfaces, including upholstery, bedding, carpets, and clothing. The only surface you should avoid is leather, as the cleaner can break down the natural oils and cause cracking.

One thing that makes this enzyme cleaner unique is the three-in-one nozzle sprayer. You can choose between foam, mist, and stream settings with just one button push. For embedded stains, we recommend using the foam setting. The mist setting is perfect for light stains, while the stream setting is ideal for odor removal.

This powerful pro-bacteria and enzyme formula is also great for preventing repeat marking. So if your dog or cat tends to pee in the same spot, this cleaner will help discourage them from going there again.

What We LikedWhat We Didn’t Like
-Three-in-one nozzle for easy application
-Eliminates tough stains and odors
-Prevents repeat marking
-Can damage leather surfaces

BUBBAS Super Strength Enzyme Cleaner  (Best for Commercial Use)

Key Features

  • Brand: BUBBA’S ROWDY FRIENDS
  • Recommended uses: Mattress, carpet, rug, sofa, laundry, hardwood floors
  • Item form: Liquid
  • Volume: 1 gallon (3,785 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Commercial enzyme cleaner

If you’re looking for a commercial-grade enzyme cleaner, you can’t go wrong with BUBBA’S Super Strength Enzyme Cleaner. A reviewer we spoke to who uses this cleaner in their professional pet-sitting business said it’s the best they’ve ever used. Our testers also found this enzyme cleaner extremely effective, even on the toughest stains and odors.

We tested this cleaner on various surfaces, including carpet, upholstery, hardwood floors, and tile. It worked great on all of them, with no adverse effects. The one caveat is that you should avoid using it on light-colored fabrics, as it may cause them to discolor. And if you’re using it on hardwoods or tiles, mix it with water first.

What sets this enzyme cleaner apart, though, is its versatility. Not only can you use it to clean up after your pets, but you can also use it to clean your laundry, carpets, and upholstery. One of our testers even used it to clean their car seats!

If you’re looking for an all-purpose enzyme cleaner that will get the job done, no matter what the job is, then BUBBA’S is the cleaner for you.

What We LikedWhat We Didn’t Like
-Effective on even the toughest stains and odors
-Multipurpose cleaner
-Great for commercial use
-Kid and pet-friendly
-May cause light-colored fabrics to discolor

ANGRY ORANGE Pet Odor Eliminator  (Best Odor Eliminator)

Key Features

  • Brand: ANGRY ORANGE
  • Recommended uses: Carpet, furniture, indoor and outdoor floors
  • Item form: Liquid
  • Volume: 24 fluid ounces (710 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: Yes
  • Cleaner type: Odor remover
  • Scent/s: Citrus scent

We all know the feeling of coming home to a house that smells like your pet has had an accident. It’s not pleasant. But with ANGRY ORANGE Pet Odor Eliminator, you can say goodbye to those nasty smells.

After testing this enzyme cleaner on various stains and odors, we can confidently say it’s one of the best odor eliminators on the market. Not only does it remove the smell of urine, but it also prevents your pet from marking the same spot again.

Moreover, this cleaner is safe on various surfaces, including carpets, upholstery, and hardwoods. When we tested it on carpets, the odor cleaner left behind a light citrus smell that was refreshing and not at all overwhelming.

ANGRY ORANGE Pet Odor Eliminator is also safe to use around pets and children. And since it’s non-toxic, you don’t have to worry about your pet ingesting harmful chemicals (as they sometimes do when licking their paws).

In short, if you’re looking for an enzyme cleaner that removes terrible smells and prevents your pet from marking the same spot again, ANGRY ORANGE is the cleaner for you.

What We LikedWhat We Didn’t Like
-Eliminates bad smells
-It prevents pets from marking the same spot again
-Safe to use around children and pets
-Non-toxic
-Expensive
-Only available in one size

Simple Solution Yard Odor Away! Hose Spray Concentrate  (Best for Outdoors)

Key Features

  • Brand: Simple Solution
  • Recommended uses: Yards
  • Item form: Liquid
  • Volume: 32 fluid ounces (946 milliliters)
  • Unit count: 1
  • Kid and Pet-friendly: No
  • Cleaner type: Odor eliminator

Last on our list of the best enzyme cleaners is Simple Solution Yard Odor Away! Hose Spray Concentrate. If your main issue is your yard smelling like cat urine, this is the product you need.

While testing this cleaner, using it as directed, we found that it could cover around 5,000 square feet (464.5 square meters). That’s a lot of yards for one bottle! So, this is an excellent option for you if you have a large yard or multiple cats that like to use your yard as their toilet.

This cleaner is super easy to use. You simply attach it to your hose, turn on the water, and let it do its thing. We also used it on an old stain, which worked just as well as on a new one.

One thing to remember with this cleaner is that it is unsafe to use around pets. So, if you have cats that like to roam the yard, you’ll need to keep them inside while using this product.

Simple Solution Yard Odor Away! Hose Spray Concentrate is an excellent value for the money. Its price point is very reasonable, especially considering how much product you get. And it does an excellent job of eliminating cat urine odor from your yard.

What We LikedWhat We Didn’t Like
-Easy to use
-Covers a large area
-Works on old and new stains
-Affordable
-Safe for plants
-Not safe around pets

Some Reader Questions Answered

How Do I Get Old or Set in Pet Stains Out of Carpet?

An enzyme cleaner is the best way to remove old or set-in pet stains from your carpet. Enzyme cleaners break down the proteins in urine, which causes stains and odors.

So, if you have an old stain you’re having trouble getting rid of, try using an enzyme cleaner. You might have to use it more than once, but eventually, the enzyme cleaner will break down all the proteins, and the stain will disappear.

Can Dry Cleaning Remove Cat Urine Odors?

Dry cleaning can remove the stain, but it will not eliminate the odor. Cat urine is very pungent, and it can be nearly impossible to eradicate the smell without using an enzyme cleaner.

So, to eliminate the odor and the stain, you’ll need to use an enzyme cleaner. But dry cleaning will do the trick if you want to remove the stain.

What Are the Different Forms of Enzymatic Cleaners?

Enzymatic cleaners come in various forms, including liquids, powders, and sprays. They also come in different sizes, so you can choose the one that best fits your needs.

Some enzymatic cleaners are also available in scented and unscented versions. So, if you’re sensitive to smells or don’t like the smell of enzymatic cleaners, you can opt for the unscented version.

What Is the Difference Between Enzymatic Cleaners and Regular Cleaning Products?

Enzymatic cleaners are different from regular cleaning products because they contain enzymes. These enzymes break down the proteins in urine, which causes the stain and odor.

Regular cleaning products don’t have enzymes, so they can’t break down the proteins in urine. That’s why enzymatic cleaners are the best option for removing pet stains and odors.

How to Use an Enzymatic Cleaner

To use an enzymatic cleaner, simply follow the instructions on the package. However, for most cleaners, you’ll need to apply the cleaner to the stain and then let it sit for a few minutes.

After a few minutes, you can blot the area with a clean cloth to remove the cleaner and the stain.

It’s important to note that you’ll usually need to use an enzymatic cleaner more than once to eradicate the stain and odor. So, don’t get discouraged if you don’t see results after the first application.

What Enzyme Breaks Down Cat Urine?

The enzymes that break down cat urine include protease, amylase, urease, lipase, and cellulase. These enzymes break down the proteins in urine into smaller molecules, eliminating the stain and odor.

What Is the Main Benefit of Using Enzyme Cleaners?

The main benefit of using enzyme cleaners is that they’re safe and effective. They’re also gentle and won’t damage your carpet or upholstery. Enzymatic cleaners are also biodegradable, so they’re better for the environment than traditional cleaners.

How Long Does It Take for an Enzyme Cleaner to Work?

It depends on your product, but most enzyme cleaners must sit for at least 10 minutes. However, some products may need to sit for up to an hour.

It’s essential to read the instructions on the product you’re using so you know how long to let it sit. It won’t be effective if you don’t let the cleaner sit long enough.

Cat urine on the carpet

Why Does Cat Pee Stink?

Cat urine contains urea, uric acid, urobilin, sodium, creatinine, pheromones, and other compounds. When the pee decomposes, bacteria break down the urea, which releases ammonia. Ammonia is a gas that has a strong, pungent odor. This is why cat urine smells so bad.

Recap

Enzymatic cleaners are the best way to remove cat urine stains and odors because they contain enzymes that break down the protein in urine. We’ve listed 13 of the best enzymatic cleaners for you to choose from. Our top pick is the Rocco & Roxie Oxy Stain Remover . It is a powerful cleaner that’s gentle and safe to use.

If you’re looking for a less expensive option the Shout Carpet Stain Remover And Odor Eliminator Spray  is an excellent choice. It’s available in a convenient spray bottle, and it’s effective at removing stains and odors.

What’s the best enzymatic cleaner for you will depend on your needs and budget. But, whichever cleaner you choose, you can be sure that it will be more effective than regular cleaning products.

Bestseller No. 2
AmazonCommercial Multi-Purpose Enzyme Cleaner,...
AmazonCommercial Multi-Purpose Enzyme Cleaner,…
Powerful enzymatic formula removes stains and odors deep in the carpet; Non-corrosive, non-flammable, non-acidic, and non-caustic with a fresh mint scent
$27.47 Amazon Prime
Bestseller No. 3
Nature's Miracle Urine Destroyer Plus for Cats,...
Nature’s Miracle Urine Destroyer Plus for Cats,…
FOR CAT URINE MESSES: Begins to break down and remove stains immediately on contact.; ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
$12.70 Amazon Prime

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